Human cRAF-RBD with N-terminal His Tag

$189.00
In stock
Catalog
P1018
Bulk Inquiry

Catalog #

Quantity

Price

P1018

0.1/0.5/1.0 mg

$189/719/1200

 

Alternative name

C-Raf Ras Binding Domain, RAF proto-oncogene serine/threonine-protein kinase, Raf1-RBD

 

Description

cRaf ( RAF proto-oncogene serine/threonine-protein kinase), also known as Rafs is a member of the Raf kinase family of serine/threonine-specific protein kinase, encoded by the raf gene in human. Raf-1 is a principal component of ERK1/2 signaling pathway. cRaf plays a role in initiating the kinase cascade as a MAP3 kinase. Ras binding process is a key step for cRaf activation involved in the cell division cycle, apoptosis, cell differentiation and cell migration.

 

Uniprot number

P04049

Expressed in

E.coli

Sequence

MHHHHHHTSNTIRV FLPNKQRTVV NVRNGMSLHD CLMKALKVRG LQPECCAVFR   
LLHEHKGKKA RLDWNTDAAS LIGEELQVDF L

 

Molecular Weight

9.8 kDa

Storage

1 year at -80°C from date of shipment.

Please avoid freeze-thaw cycles.

 

Appearance

Sterile Filtered White lyophilized (freeze-dried) powder

Formulation

Supplied as a >=5 mg/ml in 25 mM Tris-HCl, pH 8.0, 150 mM NaCl

Purity

 ≥95%, determined by SDS-PAGE

Note

For laboratory research only. Not for clinical applications.

For technical questions, please email us at support@cellron.com.

For bulk order, please contact sales@cellron.com.

 

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