Human cRAF-RBD with N-terminal His Tag

Catalog #

Quantity

Price

P1018

0.1/0.5/1.0 mg

$189/719/1200

Alternative name

C-Raf Ras Binding Domain, RAF proto-oncogene serine/threonine-protein kinase, Raf1-RBD

Description

cRaf ( RAF proto-oncogene serine/threonine-protein kinase), also known as Rafs is a member of the Raf kinase family of serine/threonine-specific protein kinase, encoded by the raf gene in human. Raf-1 is a principal component of ERK1/2 signaling pathway. cRaf plays a role in initiating the kinase cascade as a MAP3 kinase. Ras binding process is a key step for cRaf activation involved in the cell division cycle, apoptosis, cell differentiation and cell migration.

Uniprot number

P04049

Expressed in

E.coli

Sequence

Molecular Weight

9.8 kDa

Storage

1 year at -80°C from date of shipment.

Please avoid freeze-thaw cycles.

Appearance

Sterile Filtered White lyophilized (freeze-dried) powder

Formulation

Supplied as a >=5 mg/ml in 25 mM Tris-HCl, pH 8.0, 150 mM NaCl

Purity

 ≥95%, determined by SDS-PAGE

Note

For laboratory research only. Not for clinical applications.

For technical questions, please email us at support@cellron.com.

For bulk order, please contact sales@cellron.com.