CTLA-4 (recombinant human protein)
Catalog # |
Quantity |
Price |
|
P1014 |
5/25/1000 mg |
$50/130/2500 |
|
Alternative name |
CD152, IDDM12, CELIAC3, GSE, CTLA4 |
|
Description |
CTLA-4 (CD152) is a protein receptor, constitutively expressed on regulatory-T-cells. CTLA-4 plays key roles in down regulation of immune responds, and functions as an immune checkpoint. The expression of CTLA-4 is upregualted in conventional T-cells when they are activated. CTLA-4 binds with CD80 or CD86 on the presenting-antigen cells to switch “off” the immune responds. CTLA-4 (36-161aa) is expressed in E.coli, fused with an N-terminal His tag, and purified by proprietary chromatographic techniques. |
|
Uniprot number |
P16410 |
|
Expressed in |
E.coli |
|
Sequence |
MGSSHHHHHH SSGLVPRGSH MGSKAMHVAQ PAVVLASSRG IASFVCEYAS PGKATEVRVT VLRQADSQVT EVCAATYMMG NELTFLDDSI CTGTSSGNQV NLTIQGLRAM DTGLYICKVE LMYPPPYYLG IGNGTQIYVI DPEPCPDSD. |
|
Molecular Weight |
15.9 kDa |
|
Storage |
Store at -20°C |
|
Appearance |
Sterile filtered colorless solution |
|
Formulation |
1mg/ml protein in the solution containing 20mM Tris-HCl buffer (pH 8.0), 0.4M urea and 10% glycerol. |
|
Purity |
≥90%, determined by SDS-PAGE |
|
Note |
For laboratory research only. Not for clinical applications. For technical questions, please email us at support@cellron.com. For bulk order, please contact sales@cellron.com.
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