TNF alpha recombinant murine protein
Alternative name |
Tumor Necrosis Factor-α, TNF-α |
Description |
Tumor Necrosis Factor-α (TNF-α) is a potent cytokine mainly produced by macrophages, and other cells, including CD4+ lymphocytes, NK cells, neutrophils, mast cells, eosinophils, and neurons. TNF-a plays an important role in inflammation, immune modulation, antitumor activity and hematopoiesis. There are two receptors of TNF-a, TNFR1 and TNFR2. TNF- is primarily expressed as a 233aa-long transmembrane protein. Then, the soluble 17kDa TNF-a is cleaved with TNF-a converting enzyme (TACE) and forms mature and stable homotrimers.
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Uniprot number |
P06804 |
Expressed in |
E.coli |
Molecular Weight |
17.4 kDa |
Related biological data |
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Storage |
Store at -20°C |
Appearance |
Lyophilized powder |
Formulation |
Lyophilized from a solution of 5 mM Tris, pH 8.0. |
Purity |
≥95%, determined by SDS-PAGE |
Endotoxin conc.
|
<0.1 ng/mg |
Note |
For laboratory research only. Not for clinical applications. For technical questions, please email us at support@cellron.com. For bulk order, please contact sales@cellron.com.
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