TNF alpha recombinant murine protein

$160.00
In stock
Catalog
P1006
Bulk Inquiry

Alternative name

Tumor Necrosis Factor-α,  TNF-α

Description

Tumor Necrosis Factor-α (TNF-α) is a potent cytokine mainly produced by macrophages, and other cells, including CD4+ lymphocytes, NK cells, neutrophils, mast cells, eosinophils, and neurons. TNF-a plays an important role in inflammation, immune modulation, antitumor activity and hematopoiesis. There are two receptors of TNF-a, TNFR1 and TNFR2. TNF- is primarily expressed as a 233aa-long transmembrane protein. Then, the soluble 17kDa TNF-a is cleaved with TNF-a converting enzyme (TACE) and forms mature and stable homotrimers.

 

Uniprot number

P06804

Expressed in

E.coli

Molecular Weight

17.4 kDa

Related biological data

 

Storage

Store  at -20°C

Appearance

Lyophilized powder

Formulation

Lyophilized from a solution of 5 mM Tris, pH 8.0.

Purity

 ≥95%, determined by SDS-PAGE

Endotoxin conc.

 

<0.1 ng/mg

Note

For laboratory research only. Not for clinical applications.

For technical questions, please email us at support@cellron.com.

For bulk order, please contact sales@cellron.com

 

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